Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342587 | 0.93 | YAP1 (0.51) | YAP1KDM4EIL1RNERAP2ERAP1 | |
| SCHEMBL7338585 | 0.88 | UTS2R (0.57) | UTS2RCHRM2CHRM1CHRM3LMNA | |
| SCHEMBL7345278 | 0.88 | UTS2R (0.57) | UTS2RCHRM2CHRM1CHRM3LMNA | |
| SCHEMBL7367718 | 0.87 | KDM2B (0.52) | YAP1KDM2BKDM4ELTA4HEPHX2 | |
| SCHEMBL7342359 | 0.87 | YAP1 (0.55) | YAP1KDM4EIL1RNERAP2ERAP1 | |
| SCHEMBL7366593 | 0.87 | UTS2R (0.46) | YAP1KDM2BCACNA1BUTS2RCHRM2 | |
| SCHEMBL7337924 | 0.85 | YAP1 (0.56) | YAP1IL1RNERAP2ERAP1MME | |
| SCHEMBL7337102 | 0.84 | YAP1 (0.47) | YAP1KDM2BKDM4EUTS2RMME | |
| SCHEMBL7346412 | 0.83 | CACNA1B (0.59) | YAP1KDM4ECACNA1BUTS2R | |
| SCHEMBL7338808 | 0.81 | YAP1 (0.45) | YAP1IL1RNERAP2ERAP1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |