Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342585 | 0.92 | YAP1 (0.47) | YAP1LTA4HEPHX2UTS2RPPARG | |
| SCHEMBL7345272 | 0.88 | UTS2R (0.53) | YAP1UTS2RCHRM2CHRM1CHRM3 | |
| SCHEMBL7338579 | 0.88 | UTS2R (0.53) | YAP1UTS2RCHRM2CHRM1CHRM3 | |
| SCHEMBL7342356 | 0.87 | YAP1 (0.51) | YAP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7337919 | 0.86 | YAP1 (0.53) | YAP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7337109 | 0.84 | YAP1 (0.49) | YAP1KDM2BLTA4HEPHX2UTS2R | |
| SCHEMBL7367718 | 0.83 | KDM2B (0.52) | YAP1KDM2BLTA4HEPHX2KDM4E | |
| SCHEMBL7338801 | 0.82 | YAP1 (0.43) | YAP1PPARGMMEACECPA1 | |
| SCHEMBL7345870 | 0.82 | TACR2 (0.50) | PLGPRSS1PRSS2PRSS3PPARG | |
| SCHEMBL7348163 | 0.82 | PPARG (0.45) | YAP1PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |