Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.63 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.63 |
| ▸ | OXTR | P30559 | 1/20 | 0.63 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337408 | 0.88 | AVPR2 (0.49) | AVPR2AVPR1AOXTR | |
| SCHEMBL7332478 | 0.86 | AVPR2 (0.67) | AVPR2AVPR1A | |
| SCHEMBL7369344 | 0.85 | AVPR2 (0.70) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8557426 | 0.83 | NPC1 (0.49) | AVPR2AVPR1A | |
| SCHEMBL7337085 | 0.82 | AVPR2 (0.63) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8563988 | 0.80 | AVPR1A (0.58) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL7335374 | 0.80 | CHRNB2 (0.43) | AVPR2AVPR1AOXTR | |
| SCHEMBL8556495 | 0.80 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL5738340 | 0.79 | AVPR2 (0.62) | AVPR2AVPR1AOXTR | |
| SCHEMBL5739086 | 0.78 | AVPR2 (0.76) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |