Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 4/20 | 0.54 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.54 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.54 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025425 | 0.92 | HSPA5 (0.63) | HSPA5HSPA2HSPA1AHSPA9PKM | |
| SCHEMBL7344073 | 0.84 | PPARG (0.62) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7344259 | 0.84 | MEN1 (0.52) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7348738 | 0.83 | NPC1 (0.54) | PPARGMMP9MMP8HDAC6MME | |
| SCHEMBL7336531 | 0.83 | NPC1 (0.54) | PPARGMMP9MMP8HDAC6MME | |
| SCHEMBL7342788 | 0.83 | NPC1 (0.54) | PPARGMMP9MMP8HDAC6MME | |
| SCHEMBL7345065 | 0.83 | HDAC8 (0.56) | PPARGMMP9MMP8HDAC6MME | |
| SCHEMBL7338315 | 0.83 | PPARG (0.52) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7337025 | 0.83 | KLKB1 (0.52) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL7338154 | 0.82 | PPARG (0.51) | PPARGMMP9MMP8MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |