Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346029 | 0.92 | PPARG (0.49) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7339686 | 0.92 | PPARG (0.49) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7344073 | 0.89 | PPARG (0.62) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7341976 | 0.89 | PPARG (0.47) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7348064 | 0.88 | CTSL (0.42) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL7343130 | 0.88 | CTSL (0.42) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL7338315 | 0.88 | PPARG (0.52) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7337025 | 0.88 | KLKB1 (0.52) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7348198 | 0.88 | ITGA4 (0.51) | PPARG | |
| SCHEMBL7345222 | 0.87 | PPARG (0.51) | PPARGMMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |