Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020179 | 0.91 | MMP2 (0.51) | MMP1RAB9ASMN1; SMN2MMP2HTT | |
| SCHEMBL7342497 | 0.87 | MMP9 (0.48) | PPARGRAB9ANPC1MMP9MMP8 | |
| SCHEMBL7336531 | 0.86 | NPC1 (0.54) | MEN1KMT2APPARGRAB9ANPC1 | |
| SCHEMBL7345065 | 0.86 | HDAC8 (0.56) | PPARGMMP1RAB9ANPC1MMP9 | |
| SCHEMBL7348738 | 0.86 | NPC1 (0.54) | MEN1KMT2APPARGRAB9ANPC1 | |
| SCHEMBL7342788 | 0.86 | NPC1 (0.54) | MEN1KMT2APPARGRAB9ANPC1 | |
| SCHEMBL7340293 | 0.85 | NPC1 (0.52) | MEN1KMT2APPARGRAB9ANPC1 | |
| SCHEMBL7336782 | 0.85 | NPC1 (0.52) | PPARGRAB9ANPC1MMP9MMP8 | |
| SCHEMBL7340426 | 0.84 | NOX1 (0.54) | PPARGMMP1RAB9ANPC1MMP9 | |
| SCHEMBL7344073 | 0.84 | PPARG (0.62) | PPARGRAB9ANPC1MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |