Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30358044 | 0.81 | SOS1 (0.60) | CNR2DRD2CNR1P2RX3TBXA2R | |
| SCHEMBL3083259 | 0.81 | SOS1 (0.60) | CNR2DRD2CNR1P2RX3TBXA2R | |
| SCHEMBL7170787 | 0.77 | CNR2 (0.47) | CNR2CNR1TRPC5SOS1 | |
| SCHEMBL10237658 | 0.73 | CCR2 (0.52) | DRD2P2RX3KCNA3GALR3NR2F2 | |
| SCHEMBL7338096 | 0.72 | SOS1 (0.49) | CNR2CNR1P2RX3TRPC5SOS1 | |
| SCHEMBL7295346 | 0.71 | CACNA1D (0.56) | CNR2MCHR1 | |
| SCHEMBL12412028 | 0.71 | NPC1 (0.63) | CNR2CNR1RAB9ATRPC5 | |
| SCHEMBL24549318 | 0.71 | CNR2 (0.54) | CNR2CNR1RAB9A | |
| SCHEMBL7337916 | 0.70 | ALDH1A1 (0.65) | CNR2TBXA2R | |
| SCHEMBL28453413 | 0.68 | ALDH1A1 (0.63) | CNR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545845-B1 | Imidazole compounds, their preparation and use as calcium channel blockers | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | claimed |
| US-5314903-A | Benzimidazole compounds useful as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-05-24 | — | — | US | claimed |
| EP-0545845-A1 | Imidazole compounds, their preparation and use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1993-06-09 | — | — | EP | claimed |
| EP-0545845-B1 | Imidazole compounds, their preparation and use as calcium channel blockers | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5314903-A | Benzimidazole compounds useful as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-05-24 | — | — | US | disclosed |
| EP-0545845-A1 | Imidazole compounds, their preparation and use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1993-06-09 | — | — | EP | disclosed |