Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337781 | 0.98 | TP53 (0.47) | TP53GAAMAPTHTTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL7339559 | 0.97 | TP53 (0.46) | TP53GAAMAPTHTTHSP90AA1 | |
| SCHEMBL7337957 | 0.97 | TP53 (0.46) | TP53GAAMAPTHTTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL7337694 | 0.96 | TP53 (0.45) | TP53GAAMAPTHTTHSP90AA1 | |
| SCHEMBL7345808 | 0.94 | KCNMA1 (0.49) | TP53GAAMAPTHTTHSP90AA1 | |
| SCHEMBL7778655 | 0.93 | TP53 (0.42) | TP53GAAMAPTHTTHSP90AA1 | |
| SCHEMBL7340568 | 0.91 | TP53 (0.41) | TP53GAAMAPTHTTHSP90AA1 | |
| SCHEMBL7339638 | 0.91 | BRD4 (0.43) | TP53GAAMAPTHTTHSP90AA1 | |
| SCHEMBL7773802 | 0.91 | TP53 (0.41) | TP53GAAMAPTHTTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL7346913 | 0.91 | BRD4 (0.42) | TP53GAAMAPTHTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |