Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332849 | 0.90 | STAT3 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7329499 | 0.82 | KMT2A (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7333004 | 0.77 | LMNA (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7331427 | 0.76 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7342059 | 0.76 | KMT2A (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7332611 | 0.75 | LMNA (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7340439 | 0.75 | LMNA (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7330798 | 0.75 | MAPT (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7333881 | 0.75 | LMNA (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7329112 | 0.75 | LMNA (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |