Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7337646 | 0.98 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3KCNH2SIGMAR1 | |
| SCHEMBL7333053 | 0.85 | SIGMAR1 (0.45) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL7339351 | 0.84 | CXCR4 (0.54) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7338771 | 0.84 | SIGMAR1 (0.44) | SIGMAR1HRH3 | |
| SCHEMBL2109908 | 0.84 | HRH3 (0.46) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL9402131 | 0.83 | CXCR4 (0.46) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL5673726 | 0.83 | HRH3 (0.44) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL7339147 | 0.83 | KMT2A (0.49) | SIGMAR1MEN1KMT2AHRH3 | |
| SCHEMBL11342016 | 0.78 | SIGMAR1 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2SIGMAR1 | |
| SCHEMBL211040 | 0.78 | SIGMAR1 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468825-B1 | Organosilane derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZET (HU) | 1997-01-08 | — | — | EP | disclosed |
| US-5340823-A | Administering a muscle relaxants for treating parkinson*s disease | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1994-08-23 | — | — | US | disclosed |
| US-5198446-A | Muscle Relaxants | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1993-03-30 | — | — | US | disclosed |
| EP-0468825-A1 | Organosilane derivatives, pharmaceutical compositions containing them and process for preparing same | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1992-01-29 | — | — | EP | disclosed |