Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865964 | 0.67 | ELANE (0.62) | ELANE | |
| SCHEMBL7329263 | 0.67 | ELANE (0.33) | ELANE | |
| SCHEMBL7330926 | 0.65 | ELANE (0.40) | ELANE | |
| SCHEMBL10334579 | 0.52 | ALDH1A1 (0.49) | MAPT | |
| SCHEMBL784813 | 0.52 | CES1 (0.47) | ELANEKDM4EMAPT | |
| SCHEMBL22585992 | 0.51 | HRH3 (0.46) | KDM4EMAPT | |
| SCHEMBL5537289 | 0.50 | MAPT (0.53) | KDM4EMAPT | |
| SCHEMBL8324538 | 0.50 | CYP2C19 (0.48) | ELANEKDM4EMAPT | |
| SCHEMBL5666953 | 0.49 | KCNN4 (0.47) | ELANEKDM4EMAPT | |
| SCHEMBL1096837 | 0.49 | KCNN4 (0.47) | ELANEKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489604-A | TREATING DEGENERATIVE DISEASES | STERLING WINTHROP, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5385923-A | Treatment of degenerative diseases | STERLING WINTHROP INC. (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0550112-A1 | 2-Saccharinylmethyl aryl and aryloxy acetates useful as proteolytic enzyme inhibitors and pharmaceutical compositions contaning them | STERLING WINTHROP INC. (US) | 1993-07-07 | — | — | EP | disclosed |