Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329263 | 0.94 | ELANE (0.33) | ELANECHRM3 | |
| SCHEMBL7332156 | 0.69 | ELANE (0.59) | ELANECHRM3 | |
| SCHEMBL7337481 | 0.65 | ELANE (0.32) | ELANE | |
| SCHEMBL7330922 | 0.65 | ELANE (0.59) | ELANECHRM3 | |
| SCHEMBL7336876 | 0.62 | ELANE (0.51) | ELANESLC6A3CHRM3 | |
| SCHEMBL784813 | 0.58 | CES1 (0.47) | ELANE | |
| SCHEMBL9414607 | 0.56 | KEAP1 (0.45) | CHRM3 | |
| SCHEMBL8324538 | 0.56 | CYP2C19 (0.48) | ELANE | |
| SCHEMBL7347918 | 0.56 | SLC6A3 (0.33) | ELANESLC6A3CHRM3 | |
| SCHEMBL5666953 | 0.55 | KCNN4 (0.47) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783589-A | 2-saccharinylmethyl aryl and arloxy acetates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | SANOFI (FR) | 1998-07-21 | — | — | US | disclosed |
| US-5489604-A | TREATING DEGENERATIVE DISEASES | STERLING WINTHROP, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5385923-A | Treatment of degenerative diseases | STERLING WINTHROP INC. (US) | 1995-01-31 | — | — | US | disclosed |