Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337291 | 0.88 | ITGB3 (0.56) | GPR119ITGB3ITGA2BALOX15SMN1; SMN2 | |
| SCHEMBL3487761 | 0.83 | GPR119 (0.82) | GPR119ALDH1A1 | |
| SCHEMBL7338959 | 0.82 | ITGB3 (0.40) | GPR119ITGB3ITGA2BALOX15HTR4 | |
| SCHEMBL7337986 | 0.81 | GPR119 (0.50) | GPR119 | |
| SCHEMBL7345047 | 0.78 | ITGB3 (0.39) | ITGB3ITGA2BALOX15HTR4KCNH2 | |
| SCHEMBL7345347 | 0.78 | ITGB3 (0.71) | GPR119ITGB3ITGA2BALOX15MEN1 | |
| SCHEMBL7338384 | 0.76 | ITGB3 (0.54) | GPR119ITGB3ITGA2BALOX15MEN1 | |
| SCHEMBL7338379 | 0.76 | ITGB3 (0.54) | GPR119ITGB3ITGA2BALOX15MEN1 | |
| SCHEMBL7353169 | 0.75 | ITGB3 (0.53) | GPR119ITGB3ITGA2BALOX15SMN1; SMN2 | |
| SCHEMBL16824829 | 0.74 | GFER (0.53) | GPR119SMN1; SMN2MEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819113-A1 | BENZAMIDES FOR NEURODEGENERATIVE DISORDER TREATMENT | CENTAUR PHARMACEUTICALS, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031462-A1 | BENZAMIDES FOR NEURODEGENERATIVE DISORDER TREATMENT | CENTAUR PHARMACEUTICALS, INC. (US) | 1996-10-10 | — | — | WO | disclosed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |