Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 7/20 | 0.51 |
| ▸ | PLAT | P00750 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | PLG | P00747 | 4/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.45 |
| ▸ | PDE4A | P27815 | 4/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | PDE1A | P54750 | 1/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337878 | 0.84 | PLAU (0.70) | PLAUPLATF2PLGKLKB1 | |
| SCHEMBL7340961 | 0.83 | PLAU (0.70) | PLAUPLATF2PLGKLKB1 | |
| SCHEMBL7340329 | 0.78 | PLAU (0.63) | PLAUPLATF2PLGKLKB1 | |
| SCHEMBL7335937 | 0.75 | DEGS1 (0.57) | — | |
| SCHEMBL7344380 | 0.74 | PLAU (0.66) | PLAUPLATF2PLGKLKB1 | |
| SCHEMBL7345040 | 0.73 | PLAU (0.70) | PLAUPLATF2PLGKLKB1 | |
| SCHEMBL7336457 | 0.73 | NPC1 (0.53) | PLAUPLATF2PLGKLKB1 | |
| SCHEMBL7343249 | 0.72 | STAT3 (0.54) | PLAUPLATPLG | |
| SCHEMBL7336657 | 0.72 | NR1H4 (0.54) | PLAUPLATF2PLGKLKB1 | |
| SCHEMBL7336307 | 0.72 | PLAU (0.67) | PLAUPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |