Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 19/20 | 0.70 |
| ▸ | PLG | P00747 | 13/20 | 0.70 |
| ▸ | KLKB1 | P03952 | 12/20 | 0.70 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.70 |
| ▸ | F2 | P00734 | 11/20 | 0.70 |
| ▸ | PLAT | P00750 | 11/20 | 0.70 |
| ▸ | KLK1 | P06870 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337892 | 0.84 | PLAU (0.51) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7340950 | 0.83 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7856136 | 0.77 | PLAU (0.86) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7340321 | 0.75 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL8197050 | 0.75 | PDE4D (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7335930 | 0.72 | PLAU (0.78) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7344370 | 0.72 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL27536267 | 0.71 | PLAU (0.81) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7345032 | 0.71 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL13451038 | 0.71 | PARP10 (0.61) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |