Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301119 | 0.83 | NPC1 (0.57) | TSHRKMT2AHSD17B10MEN1HTT | |
| SCHEMBL28677212 | 0.79 | TDP1 (0.57) | TSHRKMT2AHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL7309905 | 0.78 | KMT2A (0.57) | TSHRKMT2AHSD17B10MEN1HTT | |
| SCHEMBL7304583 | 0.77 | KDM4E (0.44) | TSHRKMT2ASMN1; SMN2LMNAVNN1 | |
| SCHEMBL9663709 | 0.75 | CYP19A1 (0.61) | TSHRKMT2AHSD17B10MEN1HTT | |
| SCHEMBL6213582 | 0.75 | KMT2A (0.64) | TSHRKMT2AHSD17B10MEN1HTT | |
| SCHEMBL10491331 | 0.73 | SYK (0.43) | TSHRKMT2AMEN1SMN1; SMN2VNN1 | |
| SCHEMBL8138592 | 0.72 | HTR2C (0.48) | NOTUMALDH1A1MAPT | |
| SCHEMBL697595 | 0.72 | KMT2A (0.60) | KMT2AHSD17B10MEN1HTTGFER | |
| SCHEMBL27997534 | 0.72 | LMNA (0.64) | TSHRKMT2AMEN1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648497-A | Retroviral protease inhibiting compounds | ABBOTT LABORAOTRIES (US) | 1997-07-15 | — | — | US | disclosed |