Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29737271 | 0.77 | MAOA (0.52) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL1077580 | 0.77 | MAOA (0.52) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL31622921 | 0.77 | MAOA (0.52) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL2736396 | 0.77 | MAOA (0.52) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL1323794 | 0.77 | MAOA (0.52) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL4667689 | 0.77 | HTR2A (0.58) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL7452862 | 0.77 | MAOA (0.52) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL31410667 | 0.77 | MAOA (0.58) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL8820720 | 0.77 | MAOA (0.58) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL30607016 | 0.77 | MAOA (0.52) | MAOAMAOBATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707776-B1 | POSITIVE RESIST COMPOSITION, AND RESIST FILM, RESIST-COATED MASK BLANK AND RESIST PATTERN FORMING METHOD EACH USING THE COMPOSITION | FUJIFILM CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-6054448-A | TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM. | ELI LILLY AND COMPANY LIMITED (GB) | 2000-04-25 | — | — | US | disclosed |
| EP-0771196-B1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5891899-A | Pharmaceutical xanthene compounds | ELI LILLY AND COMPANY LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| EP-0849263-A2 | Pharmaceutical substituted propanoic acid derivatives | ELI LILLY AND COMPANY LIMITED (GB) | 1998-06-24 | — | — | EP | disclosed |
| EP-0837061-A1 | Pharmaceutical acidic compounds | ELI LILLY AND COMPANY LIMITED (GB) | 1998-04-22 | — | — | EP | disclosed |
| US-5717109-A | CARBOXYCYCLOPROPYL GLYCINE DERIVATIVES; USEFUL FOR TREATMENT OF ACUTE OR CHRONIC NEURODEGENERATIVE CONDITIONS, AND AS ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC, ANXIOLYTIC, ANTIDEPRESSANT AND ANTI-EMETIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |