Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 8/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338412 | 1.00 | BCL2 (0.51) | BCL2MCL1ITGA4ITGB7REN | |
| SCHEMBL7338005 | 0.91 | BCL2 (0.54) | BCL2RENIL1RNERAP2ERAP1 | |
| SCHEMBL7338014 | 0.91 | BCL2 (0.54) | BCL2RENIL1RNERAP2ERAP1 | |
| SCHEMBL7346933 | 0.90 | BCL2 (0.53) | BCL2MCL1RENIL1RNERAP2 | |
| SCHEMBL7342076 | 0.90 | ALDH1A1 (0.54) | BCL2MCL1RENIL1RNERAP2 | |
| SCHEMBL7346927 | 0.90 | BCL2 (0.53) | BCL2MCL1RENIL1RNERAP2 | |
| SCHEMBL7345731 | 0.90 | BCL2 (0.53) | BCL2MCL1RENIL1RNERAP2 | |
| SCHEMBL7342062 | 0.86 | IL1RN (0.49) | ITGA4ITGB7RENIL1RNERAP2 | |
| SCHEMBL7342058 | 0.86 | IL1RN (0.49) | ITGA4ITGB7RENIL1RNERAP2 | |
| SCHEMBL7342512 | 0.86 | CTSL (0.51) | BCL2MCL1RENIL1RNERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |