Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338599 | 1.00 | POLB (0.73) | POLBALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL7325677 | 1.00 | POLB (0.73) | POLBALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL7320484 | 0.98 | POLB (0.75) | POLBALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL6375231 | 0.87 | POLB (0.60) | POLBALDH1A1HSD17B10KMT2ACYP3A4 | |
| SCHEMBL6375227 | 0.87 | POLB (0.60) | POLBALDH1A1HSD17B10KMT2ACYP3A4 | |
| SCHEMBL9126897 | 0.86 | POLB (0.70) | POLBALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL7266801 | 0.86 | POLB (0.70) | POLBALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL7266885 | 0.86 | POLB (0.74) | POLBALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL7298853 | 0.86 | POLB (0.70) | POLBALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL7275964 | 0.86 | POLB (0.74) | POLBALDH1A1HSD17B10KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |