Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 6/20 | 0.50 |
| ▸ | ACE | P12821 | 4/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6375227 | 1.00 | POLB (0.60) | POLBFOLH1NAALAD2ALDH1A1HSD17B10 | |
| SCHEMBL7320484 | 0.88 | POLB (0.75) | POLBNAALAD2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL6368016 | 0.88 | POLB (0.60) | POLBFOLH1NAALAD2ALDH1A1KMT2A | |
| SCHEMBL4421315 | 0.88 | POLB (0.56) | POLBFOLH1NAALAD2ALDH1A1HSD17B10 | |
| SCHEMBL6368020 | 0.88 | POLB (0.60) | POLBFOLH1NAALAD2ALDH1A1KMT2A | |
| SCHEMBL4421309 | 0.88 | POLB (0.56) | POLBFOLH1NAALAD2ALDH1A1HSD17B10 | |
| SCHEMBL7338607 | 0.87 | POLB (0.73) | POLBALDH1A1HSD17B10KMT2AMME | |
| SCHEMBL7325677 | 0.87 | POLB (0.73) | POLBALDH1A1HSD17B10KMT2AMME | |
| SCHEMBL7338599 | 0.87 | POLB (0.73) | POLBALDH1A1HSD17B10KMT2AMME | |
| SCHEMBL9126897 | 0.85 | POLB (0.70) | POLBALDH1A1HSD17B10KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463135-A2 | METHODS OF EX VIVO DOSING AND ADMINISTRATION OF LIPID PARTICLES OR VIRAL VECTORS AND RELATED SYSTEMS AND USES | Sana Biotechnology, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023133595-A2 | METHODS OF EX VIVO DOSING AND ADMINISTRATION OF LIPID PARTICLES OR VIRAL VECTORS AND RELATED SYSTEMS AND USES | SANA BIOTECHNOLOGY, INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| US-6903075-B1 | Heterocyclic amide compounds as cell adhesion inhibitors | MERCK & CO., INC. (US) | 2005-06-07 | — | — | US | disclosed |
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | disclosed |