Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342095 | 0.87 | ALOX5 (0.39) | DDB1CRBNMEN1HTTGFER | |
| SCHEMBL11435272 | 0.84 | DDB1 (0.41) | DDB1CRBNKMT2A | |
| SCHEMBL1150970 | 0.83 | DDB1 (0.41) | DDB1CRBN | |
| SCHEMBL10390213 | 0.83 | HTR2A (0.43) | HTT | |
| SCHEMBL8860733 | 0.79 | DDB1 (0.38) | DDB1CRBN | |
| SCHEMBL7347613 | 0.79 | CTSK (0.33) | FFAR1MEN1KMT2A | |
| SCHEMBL7342749 | 0.77 | CTSK (0.33) | — | |
| SCHEMBL71530 | 0.77 | DDB1 (0.46) | DDB1CRBNKMT2A | |
| SCHEMBL8907523 | 0.77 | DDB1 (0.46) | DDB1CRBNKMT2A | |
| SCHEMBL1150916 | 0.76 | DDB1 (0.42) | DDB1CRBNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316906-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |