SCHEMBL7339045

SCHEMBL7339045

CC(C)(C)C1CCC(O)(O[SiH](c2ccccc2)c2ccccc2)C1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
ATM Q13315 2/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GLA P06280 1/20 0.32
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31
TRPA1 O75762 1/20 0.31
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7344540 1.00 ALDH1A1 (0.34) ALDH1A1ATMGAAKDM4EPOLB
SCHEMBL7366441 0.78 GLA (0.34) ALDH1A1ATMGAAKDM4EPOLB
SCHEMBL10437852 0.76 GLA (0.40) ALDH1A1ATMGAAKDM4EPOLB
SCHEMBL10437849 0.76 GLA (0.40) ALDH1A1ATMGAAKDM4EPOLB
SCHEMBL7344198 0.75 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL7343774 0.75 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL4113192 0.73 ALDH1A1 (0.40) ALDH1A1ATMGAAKDM4EPOLB
SCHEMBL4122288 0.73 GAA (0.39) ALDH1A1ATMGAAKDM4EPOLB
SCHEMBL27653785 0.71 ALDH1A1 (0.40) ALDH1A1ATMGAAKDM4EPOLB
SCHEMBL8464169 0.68 CYP2C9 (0.32) CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996031476-A1 AROMATIC HYDROXYETHERS RHONE-POULENC RORER LIMITED (GB) 1996-10-10 WO disclosed