SCHEMBL7344198

SCHEMBL7344198

C[SiH](C)O[C@@]1(O)CC[C@H](C(C)(C)C)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7343774 1.00 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL28468424 1.00 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL18045459 0.89
SCHEMBL6399606 0.76 EPHX1 (0.32)
SCHEMBL7339045 0.75 ALDH1A1 (0.34) ALDH1A1TDP1
SCHEMBL7344540 0.75 ALDH1A1 (0.34) ALDH1A1TDP1
SCHEMBL8596797 0.70
SCHEMBL8576107 0.70
SCHEMBL21058287 0.70
Formic Acid SCHEMBL19466603 0.68 KDM4E (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996031476-A1 AROMATIC HYDROXYETHERS RHONE-POULENC RORER LIMITED (GB) 1996-10-10 WO disclosed