Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339118 | 1.00 | DRD2 (0.67) | DRD2DRD3DRD1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7337369 | 0.99 | DRD2 (0.66) | DRD2DRD3DRD1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7337367 | 0.99 | DRD2 (0.66) | DRD2DRD3DRD1ADRA1DADRA1A | |
| SCHEMBL7333603 | 0.86 | DRD2 (0.68) | DRD2DRD3DRD1ADRA1DADRA1A | |
| SCHEMBL7333596 | 0.86 | DRD2 (0.68) | DRD2DRD3DRD1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7797087 | 0.86 | ADRA1D (0.55) | DRD2DRD3DRD1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7341908 | 0.86 | ADRA1D (0.55) | DRD2DRD3DRD1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7797081 | 0.85 | DRD2 (0.67) | DRD2DRD3DRD1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7797079 | 0.85 | DRD2 (0.67) | DRD2DRD3DRD1ADRA1DADRA1A | |
| SCHEMBL7334266 | 0.85 | DRD2 (0.69) | DRD2DRD3DRD1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781126-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008228-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.P.A. (IT) | 1996-03-21 | — | — | WO | disclosed |