Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337785 | 0.93 | MMP1 (0.52) | KDM4EPOLBMAPTMMEACE | |
| SCHEMBL7336001 | 0.88 | CACNA1B (0.52) | KDM4EPOLBMAPTMMEACE | |
| SCHEMBL7343237 | 0.88 | CACNA1B (0.60) | KDM4EPOLBMAPTCACNA1BCTSL | |
| SCHEMBL7348697 | 0.87 | CACNA1B (0.51) | MMEACECPA1ACE2CACNA1B | |
| SCHEMBL7341217 | 0.87 | TACR2 (0.50) | MAPTMMEACECPA1ACE2 | |
| SCHEMBL7340762 | 0.86 | CACNA1B (0.59) | MMEACECPA1ACE2CACNA1B | |
| SCHEMBL7343415 | 0.86 | FAAH (0.52) | KDM4EMMEACECPA1ACE2 | |
| SCHEMBL7339842 | 0.86 | CACNA1B (0.52) | KDM4EPOLBMMEACECPA1 | |
| SCHEMBL7338706 | 0.85 | CACNA1B (0.49) | MMEACECPA1ACE2CACNA1B | |
| SCHEMBL7337880 | 0.84 | CACNA1B (0.53) | MMEACECPA1ACE2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |