Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335892 | 0.88 | GPR119 (0.56) | GPR119EPHX2OXTRPDE4DPDE4A | |
| SCHEMBL7335803 | 0.87 | GPR119 (0.52) | GPR119EPHX2OXTRPDE4DPDE4A | |
| SCHEMBL8088611 | 0.87 | EPHX2 (0.57) | GPR119EPHX2ALKPDE4DPDE4A | |
| SCHEMBL7337034 | 0.87 | GPR119 (0.52) | GPR119EPHX2OXTRPDE4DPDE4A | |
| SCHEMBL7343837 | 0.83 | GPR119 (0.48) | GPR119EPHX2OXTRPDE4DPDE4A | |
| SCHEMBL5687614 | 0.80 | GPR119 (0.67) | GPR119ALKPDE4DPDE4APDE4B | |
| SCHEMBL2951108 | 0.79 | GPR119 (0.63) | GPR119EPHX2HRH3 | |
| SCHEMBL25351802 | 0.78 | GPR119 (0.57) | GPR119ALKPDE4DPDE4APDE4B | |
| SCHEMBL30535692 | 0.78 | GPR119 (0.57) | GPR119ALKPDE4DPDE4APDE4B | |
| SCHEMBL8088551 | 0.77 | EPHX2 (0.62) | GPR119EPHX2PDE4DPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5968938-A | Piperazine oxytocin receptor antagonists | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |