Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 13/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 13/20 | 0.62 |
| ▸ | OXTR | P30559 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337228 | 0.90 | AVPR2 (0.62) | AVPR1AAVPR2OXTRHPGDALDH1A1 | |
| SCHEMBL7344440 | 0.81 | AVPR2 (0.62) | AVPR1AAVPR2OXTRHPGDALDH1A1 | |
| SCHEMBL7335534 | 0.76 | AVPR2 (0.57) | AVPR1AAVPR2OXTR | |
| SCHEMBL4145691 | 0.76 | AVPR1A (0.61) | AVPR1AAVPR2OXTRHPGDALDH1A1 | |
| SCHEMBL8560249 | 0.75 | HPGD (0.53) | AVPR1AAVPR2OXTRHPGDALDH1A1 | |
| SCHEMBL3554976 | 0.72 | AVPR1A (1.00) | AVPR1AAVPR2 | |
| SCHEMBL8558207 | 0.71 | AVPR2 (0.60) | AVPR1AAVPR2OXTRHPGDALDH1A1 | |
| SCHEMBL8558342 | 0.71 | HPGD (0.48) | AVPR1AAVPR2OXTRHPGDALDH1A1 | |
| SCHEMBL4151567 | 0.71 | HTT (0.60) | AVPR1AAVPR2OXTRHPGDALDH1A1 | |
| SCHEMBL9389632 | 0.70 | AVPR2 (1.00) | AVPR1AAVPR2OXTRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008228-A | COMPRISING A MIXTURE OF CARRIER MONOGLYCERIDES OF MEDIUM CHAIN-FATTY ACIDS | HOFFMAN-LA ROCHE INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0831826-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996039142-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-12 | — | — | WO | disclosed |
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |