Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 8/20 | 0.62 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344440 | 0.91 | AVPR2 (0.62) | AVPR2AVPR1AHPGDALDH1A1OXTR | |
| SCHEMBL7339384 | 0.90 | AVPR1A (0.62) | AVPR2AVPR1AHPGDALDH1A1OXTR | |
| SCHEMBL7342110 | 0.77 | HPGD (0.63) | AVPR2AVPR1AHPGDALDH1A1OXTR | |
| SCHEMBL8560249 | 0.75 | HPGD (0.53) | AVPR2AVPR1AHPGDALDH1A1OXTR | |
| SCHEMBL3556377 | 0.72 | AVPR1A (0.81) | AVPR2AVPR1A | |
| SCHEMBL8558342 | 0.71 | HPGD (0.48) | AVPR2AVPR1AHPGDALDH1A1OXTR | |
| SCHEMBL8558207 | 0.71 | AVPR2 (0.60) | AVPR2AVPR1AHPGDALDH1A1OXTR | |
| SCHEMBL7344478 | 0.71 | P2RX4 (0.54) | AVPR2AVPR1AHPGDALDH1A1OXTR | |
| SCHEMBL8560873 | 0.71 | ACHE (0.60) | AVPR2AVPR1ARAB9A | |
| SCHEMBL8564119 | 0.69 | AVPR2 (0.68) | AVPR2AVPR1AOXTRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |