Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 17/20 | 0.54 |
| ▸ | MMP1 | P03956 | 7/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341297 | 0.83 | MMP3 (0.62) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7333431 | 0.83 | MMP3 (0.57) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7340475 | 0.82 | MMP3 (0.65) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7333213 | 0.80 | MMP3 (0.49) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6959253 | 0.77 | MMP3 (0.62) | MMP3MMP1MMP2 | |
| SCHEMBL6959258 | 0.77 | MMP3 (0.62) | MMP3MMP1MMP2 | |
| SCHEMBL7339940 | 0.75 | MMP3 (0.61) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7345078 | 0.75 | MMP3 (0.65) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6950696 | 0.75 | MMP3 (0.67) | MMP3MMP1MMP2 | |
| SCHEMBL6950694 | 0.75 | MMP3 (0.67) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847148-A | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |