Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339802 | 1.00 | HTR2A (0.42) | HTR2AHTR2CHTR2BTSHRGAA | |
| SCHEMBL7339812 | 0.82 | HTR2A (0.44) | HTR2AHTR2CHTR2BTSHRGAA | |
| SCHEMBL6196873 | 0.80 | HTR2A (0.45) | HTR2AHTR2CHTR2BTSHRGAA | |
| SCHEMBL6196869 | 0.80 | HTR2A (0.45) | HTR2AHTR2CHTR2BTSHRGAA | |
| SCHEMBL20970954 | 0.69 | HTR2A (0.79) | HTR2AHTR2CHTR2BTSHRGAA | |
| SCHEMBL7496340 | 0.69 | HTR2A (0.53) | HTR2AHTR2CHTR2BTSHRGAA | |
| SCHEMBL11039426 | 0.67 | CALM1 (0.50) | TSHRGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7155312 | 0.67 | TSHR (0.53) | HTR2AHTR2CHTR2BTSHRGAA | |
| SCHEMBL6896899 | 0.67 | TSHR (0.52) | HTR2AHTR2CHTR2BTSHRGAA | |
| SCHEMBL11392849 | 0.66 | HTR2A (0.50) | HTR2AHTR2CHTR2BTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514401-A | CARDIOTONICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-04-30 | — | — | US | disclosed |