Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.53 |
| ▸ | RRM1 | P23921 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750775 | 1.00 | CASP2 (0.55) | CASP2NOD1DPP7RRM1GRIK1 | |
| SCHEMBL24696810 | 1.00 | CASP2 (0.55) | CASP2NOD1DPP7RRM1GRIK1 | |
| SCHEMBL15986222 | 0.91 | EPHX2 (0.59) | — | |
| SCHEMBL15986221 | 0.91 | EPHX2 (0.59) | — | |
| SCHEMBL3795617 | 0.86 | DPP7 (0.67) | CASP2NOD1DPP7RRM1NAAA | |
| SCHEMBL29238181 | 0.86 | DPP7 (0.67) | CASP2NOD1DPP7RRM1NAAA | |
| SCHEMBL3791159 | 0.86 | DPP7 (0.67) | CASP2NOD1DPP7RRM1NAAA | |
| SCHEMBL31283221 | 0.86 | DPP7 (0.67) | CASP2NOD1DPP7RRM1NAAA | |
| SCHEMBL3798623 | 0.86 | DPP7 (0.67) | CASP2NOD1DPP7RRM1NAAA | |
| SCHEMBL12283211 | 0.86 | CASP2 (0.55) | CASP2DPP7RRM1NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580923-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2012-10-18 | — | — | US | disclosed |
| US-8138140-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2012-03-20 | — | — | US | disclosed |
| EP-1696945-B1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | UNIV NORTHWESTERN (US) | 2012-01-18 | — | — | EP | disclosed |
| CN-102225964-A | Self-assembling peptide amphiphiles and related methods for growth factor delivery | UNIV NORTHWESTERN | 2011-10-26 | — | — | CN | disclosed |
| EP-2314305-A2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | Northwestern University (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| US-7544661-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2009-06-09 | — | — | US | disclosed |
| EP-1696945-A4 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | UNIV NORTHWESTERN (US) | 2007-03-21 | — | — | EP | disclosed |
| CN-1905892-A | Self-assembling peptide amphiphiles and related methods for growth factor delivery | UNIV NORTHWESTERN (US) | 2007-01-31 | — | — | CN | disclosed |
| EP-1696945-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2006-09-06 | — | — | EP | disclosed |
| US-20050209145-A1 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | ENERGY, UNITED STATES DEPARTMENT OF | 2005-09-22 | — | — | US | disclosed |
| WO-2005056039-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | HDGF, HDGFL3, IAPP | CASP2 2283/4885NOD1 2778/4885DPP7 818/4885 |
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | HDGF, HDGFL3, IAPP | CASP2 2283/4885NOD1 2778/4885DPP7 818/4885 |
| US-20050209145-A1 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | HDGF, HDGFL3, IAPP | CASP2 2283/4885NOD1 2778/4885DPP7 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.