Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339789 | 0.86 | CA12 (0.39) | ALDH1A1LMNATSHRCA12CA1 | |
| SCHEMBL7778599 | 0.86 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1LMNATSHRDRD2 | |
| SCHEMBL7342217 | 0.83 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1LMNATSHRDRD2 | |
| SCHEMBL7344657 | 0.83 | CA12 (0.39) | LMNACA12CA1CA2CA9 | |
| SCHEMBL7345667 | 0.83 | DRD2 (0.37) | DRD2CA12CA1CA2CA9 | |
| SCHEMBL7338860 | 0.82 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1TSHRDRD2AVPR2 | |
| SCHEMBL7345518 | 0.82 | SIGMAR1 (0.38) | SIGMAR1ALDH1A1TSHRDRD2AVPR2 | |
| SCHEMBL7340239 | 0.82 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1TSHRDRD2AVPR2 | |
| SCHEMBL7340053 | 0.82 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1TSHRDRD2AVPR2 | |
| SCHEMBL7343781 | 0.81 | SIGMAR1 (0.35) | SIGMAR1ALDH1A1LMNATSHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |