Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374343 | 0.88 | NAMPT (0.58) | PPIAKMT2A | |
| SCHEMBL7337256 | 0.88 | L3MBTL1 (0.48) | PPIAMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7368777 | 0.83 | MEN1 (0.42) | PPIAMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7349946 | 0.81 | L3MBTL1 (0.46) | PPIAL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7341616 | 0.81 | L3MBTL1 (0.45) | PPIAKMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL7349032 | 0.81 | L3MBTL1 (0.46) | PPIAL3MBTL1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7340336 | 0.80 | KDR (0.52) | PPIAL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7343900 | 0.80 | KMT2A (0.47) | PPIAMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7366121 | 0.79 | SMN1; SMN2 (0.57) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL7339623 | 0.79 | L3MBTL1 (0.46) | PPIAL3MBTL1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |