Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 13/20 | 0.44 |
| ▸ | PLG | P00747 | 8/20 | 0.35 |
| ▸ | KLK1 | P06870 | 8/20 | 0.35 |
| ▸ | PLAT | P00750 | 6/20 | 0.35 |
| ▸ | F12 | P00748 | 2/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499445 | 0.88 | PLAU (0.35) | PLAUPLGKLK1PLATCYP1A1 | |
| SCHEMBL7336146 | 0.83 | PLAU (0.46) | PLAUPLGKLK1PLATCYP1A1 | |
| SCHEMBL7345650 | 0.79 | F9 (0.40) | PLAUPLGF2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7340240 | 0.78 | PLAU (0.64) | PLAUPLGKLK1PLATF12 | |
| SCHEMBL7342370 | 0.76 | PLAU (0.46) | PLAUPLGKLK1PLATCYP1A1 | |
| SCHEMBL7335067 | 0.76 | ASIC3 (0.46) | PLAUCYP1A1CYP1B1PLA2G2D | |
| SCHEMBL7337460 | 0.76 | PLAU (0.32) | PLAUALDH1A1MAPT | |
| SCHEMBL7335720 | 0.76 | PLG (0.34) | PLAUPLGKLK1PLATCYP1A1 | |
| SCHEMBL7337120 | 0.75 | PLAU (0.48) | PLAUPLGKLK1PLAT | |
| SCHEMBL7344312 | 0.74 | F2 (0.44) | PLAUPLGKLK1PLATF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |