Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343940 | 0.94 | ALDH1A1 (0.54) | SMN1; SMN2MAPTRAB9AALDH1A1TSHR | |
| SCHEMBL7340478 | 0.91 | HSD17B10 (0.60) | SMN1; SMN2RAB9AALDH1A1TSHRHSD17B10 | |
| SCHEMBL10495302 | 0.85 | ALDH1A1 (0.70) | SMN1; SMN2MAPTRAB9AALDH1A1TSHR | |
| SCHEMBL10555513 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTRAB9AALDH1A1TSHR | |
| SCHEMBL7347999 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTRAB9AALDH1A1TSHR | |
| SCHEMBL30855594 | 0.82 | CYP1A2 (0.57) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL7346924 | 0.82 | CYP1A2 (0.57) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL28801777 | 0.81 | ALDH1A1 (0.64) | SMN1; SMN2MAPTRAB9AALDH1A1TSHR | |
| SCHEMBL9839694 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTRAB9AALDH1A1TSHR | |
| SCHEMBL10767291 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833150-A | HYPOTENSIVES, ANTIARRHYTHMIA AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4652573-A | HYPOTENSIVE AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0194685-A1 | 1,4-Dihydropyridines | Whitby Research Incorporated (US) | 1986-09-17 | — | — | EP | disclosed |