Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336536 | 0.90 | LTA4H (0.59) | LTA4HNPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL7345070 | 0.90 | HDAC8 (0.60) | LTA4HNPC1RAB9ASMN1; SMN2IL1RN | |
| SCHEMBL7348742 | 0.90 | LTA4H (0.59) | LTA4HNPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL7342789 | 0.89 | LTA4H (0.58) | LTA4HNPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL7340297 | 0.88 | LTA4H (0.57) | LTA4HNPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL7336784 | 0.88 | LTA4H (0.57) | LTA4HNPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL7342507 | 0.85 | LTA4H (0.52) | LTA4HNPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL7345571 | 0.84 | LTA4H (0.52) | LTA4HNPC1RAB9ASMN1; SMN2MMP9 | |
| SCHEMBL7336922 | 0.83 | CACNA1B (0.62) | NOX1 | |
| SCHEMBL7344263 | 0.83 | MEN1 (0.55) | LTA4HNPC1RAB9ASMN1; SMN2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |