Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TACR2 | P21452 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344689 | 0.89 | CACNA1B (0.59) | CTSLCTSKMAPTKDM4ECACNA1B | |
| SCHEMBL7336536 | 0.87 | LTA4H (0.59) | LTA4HKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7345070 | 0.87 | HDAC8 (0.60) | LTA4HCTSKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7348742 | 0.87 | LTA4H (0.59) | LTA4HKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7342789 | 0.86 | LTA4H (0.58) | LTA4HKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7336784 | 0.85 | LTA4H (0.57) | LTA4HKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7340297 | 0.85 | LTA4H (0.57) | LTA4HKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7340430 | 0.84 | NOX1 (0.58) | LTA4HKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7340762 | 0.84 | CACNA1B (0.59) | CACNA1B | |
| SCHEMBL7345567 | 0.83 | RAB9A (0.48) | LTA4HCTSLCTSKKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |