Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11496011 | 0.98 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL11492702 | 0.98 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| Pyrrole SCHEMBL11495979 | 0.92 | ALDH1A1 (0.62) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11494244 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11486462 | 0.91 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11496009 | 0.87 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11483915 | 0.87 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL9823429 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL11492701 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11370644 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPK1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107441497-A | A kind of A Lishatan esters solid dispersions and preparation method thereof and the preparation containing the solid dispersions | 深圳信立泰药业股份有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-107441048-A | A kind of A Lishatan esters pharmaceutical composition and the preparation containing the pharmaceutical composition and preparation method thereof | 深圳信立泰药业股份有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-106188012-A | A kind of A Lishatan ester crystallization and preparation method thereof and the pharmaceutical composition containing this crystallization | 深圳信立泰药业股份有限公司 | 2016-12-07 | — | — | CN | disclosed |
| EP-0503785-B1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |
| EP-0545912-B1 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |
| EP-0573218-B1 | 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use | SANKYO CO (JP) | 2001-03-07 | — | — | EP | disclosed |
| CN-1045770-C | Process for preparing 1-biphenylmethylimidazole derivatives | SANKYO CO (JP) | 1999-10-20 | — | — | CN | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0573218-A2 | 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0545912-A2 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0000373-B1 | IMIDAZOLE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULANTS OR PLANT PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-07 | — | — | EP | disclosed |
| US-4182624-A | FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |
| EP-0000373-A1 | Imidazole carboxylic acids and derivatives thereof, process for their preparation and their use as plant growth regulants or plant protection agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-24 | — | — | EP | disclosed |