Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823389 | 0.86 | MAPK1 (0.62) | ALDH1A1TDP1MAPK1OPRM1OPRD1 | |
| SCHEMBL7340516 | 0.85 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPK1OPRD1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11492702 | 0.84 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1OPRD1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11496011 | 0.84 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1OPRD1CYP1A2 | |
| SCHEMBL9823499 | 0.81 | OPRK1 (0.40) | ALDH1A1TDP1MAPK1OPRM1OPRD1 | |
| SCHEMBL9823442 | 0.80 | MAPK1 (0.42) | ALDH1A1TDP1MAPK1OPRM1OPRD1 | |
| Pyrrole SCHEMBL11495979 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TDP1MAPK1OPRD1CYP1A2 | |
| SCHEMBL11494244 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1CYP1A2GABRA1 | |
| SCHEMBL11486462 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1CYP1A2GABRA1 | |
| SCHEMBL9823270 | 0.76 | OPRK1 (0.42) | ALDH1A1TDP1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4770689-A | TRANSPLANTED RICE AND MAIZE CROPS | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-09-13 | — | — | US | claimed |
| EP-0240050-A1 | A method for controlling weeds | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-10-07 | — | — | EP | claimed |
| CN-1023317-C | Method for controlling weeds | JASSEN PHARMACEUTIC N V (BE) | 1993-12-29 | — | — | CN | disclosed |
| EP-0240050-B1 | A METHOD FOR CONTROLLING WEEDS | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-06-26 | — | — | EP | disclosed |
| US-4770689-A | TRANSPLANTED RICE AND MAIZE CROPS | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-09-13 | — | — | US | disclosed |
| EP-0240050-A1 | A method for controlling weeds | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-10-07 | — | — | EP | disclosed |
| CN-87101880-A | METHOD FOR CONTROLLING WEEDS | — | 1987-09-23 | — | — | CN | disclosed |