Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | HMGCR | P04035 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322168 | 0.85 | CTSD (0.62) | LMNAHSD17B10HTTALOX15CHRM1 | |
| SCHEMBL29658169 | 0.85 | CTSD (0.62) | LMNAHSD17B10HTTALOX15CHRM1 | |
| SCHEMBL29229967 | 0.84 | MAPT (0.70) | LMNACYP3A4HPGDMAPTHSD17B10 | |
| SCHEMBL4060271 | 0.84 | LMNA (0.62) | LMNACYP3A4HPGDMAPTHSD17B10 | |
| SCHEMBL30320256 | 0.83 | LMNA (0.62) | LMNACYP3A4HPGDMAPTHSD17B10 | |
| SCHEMBL5709859 | 0.83 | LMNA (0.62) | LMNACYP3A4HPGDMAPTHSD17B10 | |
| SCHEMBL27789892 | 0.83 | CTSD (0.60) | LMNAHSD17B10HTTALOX15STS | |
| Bicarbonate SCHEMBL10930728 | 0.83 | LMNA (0.52) | LMNACYP3A4HPGDMAPTHSD17B10 | |
| SCHEMBL9339940 | 0.83 | MAPT (0.84) | LMNACYP3A4HPGDMAPTHSD17B10 | |
| SCHEMBL3818697 | 0.83 | KDM4E (0.59) | LMNAHPGDHSD17B10KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981774-A | PREPARING 3,5-DI(2,3-EPOXYPROPOXY)-1-HYDROXYXANTHONE BY REACTING 1,3,5-TRIMETHOXYXANTHONE WITH HYDROGEN IODIDE IN PHENOL WHEREBY 1,3,5-TRIHYDROXYXANTHONE IS OBTAINED, REACTING PRODUCT WITH EPICHLOROHYDRIN IN POTASSIUM HYDROXIDE | NATIONAL SCIENCE COUNCIL (TW) | 1999-11-09 | — | — | US | disclosed |
| US-5741813-A | ADMINISTERING SUBSTITUTED XANTHONES | NATIONAL SCIENCE COUNCIL (TW) | 1998-04-21 | — | — | US | disclosed |
| US-5495005-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | NATIONAL SCIENCE COUNCIL (TW) | 1996-02-27 | — | — | US | disclosed |