Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 13/20 | 0.62 |
| ▸ | CA9 | Q16790 | 13/20 | 0.62 |
| ▸ | CA1 | P00915 | 5/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337436 | 0.82 | GAA (0.55) | ALDH1A1HTTL3MBTL1KMT2APKM | |
| SCHEMBL7829254 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTL3MBTL1KMT2APKM | |
| SCHEMBL7065442 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HTTL3MBTL1KMT2APKM | |
| SCHEMBL7071220 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HTTL3MBTL1KMT2APKM | |
| SCHEMBL7337708 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HTTL3MBTL1KMT2APKM | |
| SCHEMBL19500873 | 0.77 | KMT2A (1.00) | ALDH1A1HTTL3MBTL1KMT2APKM | |
| SCHEMBL30527996 | 0.76 | CA12 (1.00) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL1172438 | 0.76 | CA12 (1.00) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL7069708 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HTTL3MBTL1KMT2APKM | |
| SCHEMBL7068590 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HTTL3MBTL1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811001-B1 | BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS | WARNER LAMBERT CO (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-1996026195-A1 | BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-08-29 | — | — | WO | disclosed |