Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 5/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESRRB | O95718 | 3/20 | 0.38 |
| ▸ | ESRRA | P11474 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337962 | 0.94 | ITGB3 (0.68) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7345194 | 0.88 | ITGB3 (0.62) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7340673 | 0.88 | ITGB3 (0.50) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7340646 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7310389 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7344004 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7334802 | 0.83 | ITGB3 (0.87) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL9368133 | 0.82 | ITGB3 (0.50) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7346154 | 0.82 | ITGB3 (0.67) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7334894 | 0.81 | ITGB3 (0.69) | ITGB3ITGA2BALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |