Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.87 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.87 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.85 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839445 | 0.93 | ITGB3 (1.00) | ITGB3ITGA2BALOX15F2PRSS1 | |
| Hydrochloric Acid SCHEMBL8431411 | 0.91 | ALOX15 (0.98) | ITGB3ITGA2BALOX15F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7341381 | 0.88 | ITGB3 (0.68) | ITGB3ITGA2BALOX15F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7342483 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BALOX15F2 | |
| Trifluoroacetic Acid SCHEMBL7347536 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BALOX15F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7340646 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7339460 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BALOX15 | |
| SCHEMBL7336167 | 0.85 | ITGB3 (0.69) | ITGB3ITGA2BALOX15F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL9372077 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BALOX15F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7345194 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847148-A | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |