Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.70 |
| ▸ | ACE | P12821 | 4/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 12/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340777 | 1.00 | ITGB3 (0.70) | ITGB3ITGA2BACEGABRPGABRD | |
| Hydrochloric Acid SCHEMBL8622679 | 0.99 | ITGB3 (0.69) | ITGB3ITGA2BACEGABRPGABRD | |
| Hydrochloric Acid SCHEMBL8622674 | 0.99 | ITGB3 (0.69) | ITGB3ITGA2BACEGABRPGABRD | |
| SCHEMBL7320593 | 0.84 | ACE (0.56) | ITGB3ITGA2BACE | |
| SCHEMBL7405338 | 0.84 | ACE (0.56) | ITGB3ITGA2BACE | |
| SCHEMBL8621118 | 0.74 | ITGB3 (0.49) | ITGB3ITGA2BGABRPGABRDGABRA1 | |
| SCHEMBL8621921 | 0.73 | ITGB3 (0.58) | ITGB3ITGA2BF11 | |
| SCHEMBL8623903 | 0.71 | ITGB3 (0.52) | ITGB3ITGA2BGABRPGABRDGABRA1 | |
| SCHEMBL7344183 | 0.70 | ITGB3 (0.45) | ITGB3ITGA2BF11 | |
| SCHEMBL8830082 | 0.69 | ITGB3 (0.63) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |