Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320593 | 1.00 | ACE (0.56) | ACEITGB3ITGA2BCYP19A1ITGAV | |
| SCHEMBL7340777 | 0.84 | ITGB3 (0.70) | ACEITGB3ITGA2B | |
| SCHEMBL7340771 | 0.84 | ITGB3 (0.70) | ACEITGB3ITGA2B | |
| SCHEMBL8830082 | 0.83 | ITGB3 (0.63) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL8622679 | 0.83 | ITGB3 (0.69) | ACEITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8622674 | 0.83 | ITGB3 (0.69) | ACEITGB3ITGA2B | |
| SCHEMBL7349976 | 0.80 | ITGB3 (0.65) | ITGB3ITGA2BITGAV | |
| SCHEMBL7371956 | 0.80 | ITGB3 (0.65) | ITGB3ITGA2BITGAV | |
| SCHEMBL7371673 | 0.80 | ITGB3 (0.51) | ACEITGB3ITGA2BKDM4EMEN1 | |
| SCHEMBL7371068 | 0.79 | ITGB3 (0.63) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |