Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.76 |
| ▸ | PDE4A | P27815 | 5/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858838 | 0.90 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL1026961 | 0.87 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1031648 | 0.82 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7343356 | 0.81 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7356316 | 0.81 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8554187 | 0.81 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL1434462 | 0.80 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1030283 | 0.79 | PDE4D (0.67) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9278461 | 0.79 | PDE4D (0.63) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6858835 | 0.79 | PDE4D (0.63) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031476-A1 | AROMATIC HYDROXYETHERS | RHONE-POULENC RORER LIMITED (GB) | 1996-10-10 | — | — | WO | disclosed |