Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.40 |
| ▸ | CBX7 | O95931 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452056 | 0.88 | MCL1 (0.52) | KMT2AMEN1RAB9ANPC1HDAC8 | |
| SCHEMBL7412830 | 0.87 | MEN1 (0.41) | KMT2AMEN1RAB9ANPC1HDAC8 | |
| SCHEMBL8342543 | 0.86 | KMT2A (0.50) | KMT2AMEN1RAB9ANPC1HDAC8 | |
| SCHEMBL7966118 | 0.85 | SMN1; SMN2 (0.52) | KMT2AMEN1RAB9ANPC1HDAC8 | |
| SCHEMBL7351054 | 0.85 | SMN1; SMN2 (0.50) | KMT2AMEN1RAB9ANPC1HDAC8 | |
| SCHEMBL7343350 | 0.85 | SMN1; SMN2 (0.44) | KMT2AMEN1RAB9ANPC1HDAC8 | |
| SCHEMBL7443547 | 0.83 | PPARG (0.44) | KMT2AMEN1RAB9ANPC1HDAC8 | |
| SCHEMBL2157110 | 0.81 | RAB9A (0.53) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7371023 | 0.78 | SMN1; SMN2 (0.48) | KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7665668 | 0.77 | KCNQ3 (0.46) | RAB9ASMN1; SMN2POLBCISD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932582-A | Fibrinogen receptor antagonist prodrugs | MERCK & CO., INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0912513-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000401-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |