Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794191 | 0.86 | CYP17A1 (0.49) | KCNQ3KCNQ2DHODHKDRBRAF | |
| SCHEMBL6754908 | 0.86 | KCNQ3 (0.46) | KCNQ3KCNQ2ALDH1A1POLBGAA | |
| SCHEMBL5151209 | 0.85 | TRPV1 (0.42) | KCNQ3KCNQ2DHODHSMN1; SMN2CISD2 | |
| SCHEMBL5563026 | 0.85 | KCNQ3 (0.45) | KCNQ3KCNQ2ALDH1A1POLBGAA | |
| SCHEMBL2157110 | 0.84 | RAB9A (0.53) | GAATHRBSMN1; SMN2CISD2RAB9A | |
| SCHEMBL7383350 | 0.84 | DHODH (0.51) | DHODHKDRBRAFALDH1A1POLB | |
| SCHEMBL17295021 | 0.84 | IGF2BP2 (0.46) | KCNQ3KCNQ2ALDH1A1POLBGAA | |
| SCHEMBL687475 | 0.84 | IGF2BP2 (0.58) | KCNQ3KCNQ2DHODHALDH1A1POLB | |
| SCHEMBL31135377 | 0.83 | BRAF (0.47) | KCNQ3KCNQ2KDRBRAFALDH1A1 | |
| SCHEMBL3427482 | 0.83 | KCNQ3 (0.43) | KCNQ3KCNQ2ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |