Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345445 | 0.95 | ALDH1A1 (0.69) | HTR2CALDH1A1KMT2ATP53 | |
| SCHEMBL7342907 | 0.95 | ALDH1A1 (0.72) | HTR2CALDH1A1KMT2ATP53 | |
| SCHEMBL7347004 | 0.94 | KMT2A (0.73) | HTR2CALDH1A1KMT2ATP53 | |
| SCHEMBL7345568 | 0.86 | ALDH1A1 (0.69) | HTR2CALDH1A1KMT2A | |
| SCHEMBL7347595 | 0.84 | ALDH1A1 (0.67) | HTR2CALDH1A1KMT2A | |
| SCHEMBL10844118 | 0.83 | HTR2C (1.00) | HTR2CTP53MAPTRXFP1 | |
| SCHEMBL10849241 | 0.82 | HTR2C (0.78) | HTR2CTP53MAPTRXFP1 | |
| SCHEMBL10846873 | 0.80 | HTR2C (0.74) | HTR2CTP53 | |
| SCHEMBL7342568 | 0.80 | MAPT (0.77) | HTR2CTP53MAPTRXFP1 | |
| SCHEMBL7349861 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KMT2ATP53MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780464-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-25 | — | — | US | disclosed |