Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | TOP2A | P11388 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347595 | 0.93 | ALDH1A1 (0.67) | ALDH1A1KMT2AHTR2CADORA3ADORA1 | |
| SCHEMBL7342907 | 0.91 | ALDH1A1 (0.72) | ALDH1A1KMT2AHTR2C | |
| SCHEMBL7347004 | 0.90 | KMT2A (0.73) | ALDH1A1KMT2AHTR2C | |
| SCHEMBL7345445 | 0.88 | ALDH1A1 (0.69) | ALDH1A1KMT2AHTR2C | |
| SCHEMBL7340843 | 0.86 | HTR2C (0.70) | ALDH1A1KMT2AHTR2C | |
| SCHEMBL7349861 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KMT2AADORA3ADORA1TOP2A | |
| SCHEMBL7343252 | 0.77 | ALDH1A1 (0.69) | ALDH1A1KMT2AADORA3ADORA1TOP2A | |
| SCHEMBL29406615 | 0.76 | ALDH1A1 (0.72) | ALDH1A1KMT2AADORA3ADORA1TOP2A | |
| SCHEMBL8118878 | 0.76 | ALDH1A1 (0.72) | ALDH1A1KMT2AADORA3ADORA1TOP2A | |
| SCHEMBL14765127 | 0.75 | PDE2A (0.53) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780464-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-25 | — | — | US | disclosed |